4rau

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'''Unreleased structure'''
 
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The entry 4rau is ON HOLD until Paper Publication
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==crystal structure of RTOFab in complex with human PF4==
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<StructureSection load='4rau' size='340' side='right' caption='[[4rau]], [[Resolution|resolution]] 3.74&Aring;' scene=''>
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Authors: Cai, Z., Zhu, Z., Liu, Q., Greene, M.I.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4rau]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RAU FirstGlance]. <br>
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Description: crystal structure of RTOFab in complex with human PF4
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rau OCA], [http://pdbe.org/4rau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rau RCSB], [http://www.ebi.ac.uk/pdbsum/4rau PDBsum]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Greene, M.I]]
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== Function ==
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[[http://www.uniprot.org/uniprot/PLF4_HUMAN PLF4_HUMAN]] Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.<ref>PMID:7644496</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Cai, Z]]
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[[Category: Greene, M I]]
[[Category: Liu, Q]]
[[Category: Liu, Q]]
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[[Category: Cai, Z]]
 
[[Category: Zhu, Z]]
[[Category: Zhu, Z]]
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[[Category: Antibody]]
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[[Category: Antigen]]
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[[Category: Blood]]
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[[Category: Cxc chemokine]]
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[[Category: Hit]]
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[[Category: Immune system]]
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[[Category: Immunoglobulin]]
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[[Category: Pf4]]
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[[Category: Rto]]

Revision as of 03:42, 11 May 2016

crystal structure of RTOFab in complex with human PF4

4rau, resolution 3.74Å

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