4yqf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 4yqf is ON HOLD until Mar 13 2017
+
==GTPase domain of Human Septin 9==
-
 
+
<StructureSection load='4yqf' size='340' side='right' caption='[[4yqf]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
-
Authors: Matos, S.O., Leonardo, D.A., Macedo, J.N., Pereira, H.M., Araujo, A.P.U., Garratt, R.C.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4yqf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YQF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YQF FirstGlance]. <br>
-
Description: GTPase domain of Human Septin 9
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yqf OCA], [http://pdbe.org/4yqf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yqf RCSB], [http://www.ebi.ac.uk/pdbsum/4yqf PDBsum]</span></td></tr>
-
[[Category: Leonardo, D.A]]
+
</table>
-
[[Category: Garratt, R.C]]
+
== Disease ==
-
[[Category: Pereira, H.M]]
+
[[http://www.uniprot.org/uniprot/SEPT9_HUMAN SEPT9_HUMAN]] Neuralgic amyotrophy. A chromosomal aberration involving SEPT9/MSF is found in therapy-related acute myeloid leukemia (t-AML). Translocation t(11;17)(q23;q25) with KMT2A/MLL1.<ref>PMID:10339604</ref> The disease is caused by mutations affecting the gene represented in this entry.
-
[[Category: Araujo, A.P.U]]
+
== Function ==
-
[[Category: Macedo, J.N]]
+
[[http://www.uniprot.org/uniprot/SEPT9_HUMAN SEPT9_HUMAN]] Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
-
[[Category: Matos, S.O]]
+
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Araujo, A P.U]]
 +
[[Category: Garratt, R C]]
 +
[[Category: Leonardo, D A]]
 +
[[Category: Macedo, J N]]
 +
[[Category: Matos, S O]]
 +
[[Category: Pereira, H M]]
 +
[[Category: Cytoskeleton component. septin gtpase]]
 +
[[Category: Hydrolase]]

Revision as of 03:45, 11 May 2016

GTPase domain of Human Septin 9

4yqf, resolution 2.73Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools