4yu1
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Human Aldose Reductase complexed with Schl12134 (3-[5-(3-nitrophenyl)-2-thienyl]propanoic acid) at 1.02 A== | |
| - | + | <StructureSection load='4yu1' size='340' side='right' caption='[[4yu1]], [[Resolution|resolution]] 1.02Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4yu1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YU1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YU1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=53N:3-[5-(3-NITROPHENYL)THIOPHEN-2-YL]PROPANOIC+ACID'>53N</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ikg|2ikg]], [[2ikh|2ikh]], [[3dn5|3dn5]], [[4nkc|4nkc]], [[4pr4|4pr4]], [[4prr|4prr]], [[4prt|4prt]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yu1 OCA], [http://pdbe.org/4yu1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yu1 RCSB], [http://www.ebi.ac.uk/pdbsum/4yu1 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN]] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aldehyde reductase]] | ||
[[Category: Heine, A]] | [[Category: Heine, A]] | ||
| + | [[Category: Klebe, G]] | ||
[[Category: Rechlin, C]] | [[Category: Rechlin, C]] | ||
| - | [[Category: | + | [[Category: Oxidoreductase]] |
| + | [[Category: Protein-ligand-complex]] | ||
| + | [[Category: Tim-barrel]] | ||
Revision as of 12:57, 11 May 2016
Human Aldose Reductase complexed with Schl12134 (3-[5-(3-nitrophenyl)-2-thienyl]propanoic acid) at 1.02 A
| |||||||||||
