5em4
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of CYP2B4 F244W in a ligand free conformation== | |
| - | + | <StructureSection load='5em4' size='340' side='right' caption='[[5em4]], [[Resolution|resolution]] 3.02Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5em4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EM4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EM4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CM5:5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE'>CM5</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tmz|3tmz]], [[2bdm|2bdm]], [[1po5|1po5]], [[3uas|3uas]], [[3mvr|3mvr]], [[2q6n|2q6n]], [[3me6|3me6]], [[3kw4|3kw4]], [[3tk3|3tk3]], [[4h1n|4h1n]], [[1suo|1suo]], [[3r1a|3r1a]], [[3r1b|3r1b]], [[3g93|3g93]], [[3g5n|3g5n]], [[4jlt|4jlt]]</td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5em4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5em4 OCA], [http://pdbe.org/5em4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5em4 RCSB], [http://www.ebi.ac.uk/pdbsum/5em4 PDBsum]</span></td></tr> |
| - | [[Category: Stout, C | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CP2B4_RABIT CP2B4_RABIT]] Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it has a unique preference for the 5,6-olefin. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Unspecific monooxygenase]] | ||
| + | [[Category: Halpert, J R]] | ||
| + | [[Category: Shah, M B]] | ||
| + | [[Category: Stout, C D]] | ||
| + | [[Category: Cytochrome p450]] | ||
| + | [[Category: Monooxygenase]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 13:03, 11 May 2016
Structure of CYP2B4 F244W in a ligand free conformation
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