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4y22
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Complex of human Galectin-1 and (3OSO3)Galbeta1-3GlcNAc== | |
| - | + | <StructureSection load='4y22' size='340' side='right' caption='[[4y22]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4y22]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y22 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MAG:BETA-METHYL-N-ACETYL-D-GLUCOSAMINE'>MAG</scene>, <scene name='pdbligand=SGA:O3-SULFONYLGALACTOSE'>SGA</scene></td></tr> | |
| - | [[ | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> |
| - | [[Category: Hsieh, T | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y20|4y20]], [[4y1z|4y1z]], [[4y1x|4y1x]], [[4y1v|4y1v]], [[4y1u|4y1u]], [[4y1y|4y1y]], [[4y24|4y24]], [[4y26|4y26]]</td></tr> |
| - | [[Category: Lin, H | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y22 OCA], [http://pdbe.org/4y22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y22 RCSB], [http://www.ebi.ac.uk/pdbsum/4y22 PDBsum]</span></td></tr> |
| - | [[Category: Lin, | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Hsieh, T J]] | ||
| + | [[Category: Lin, C H]] | ||
| + | [[Category: Lin, H Y]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Galectin-1]] | ||
| + | [[Category: Sugar binding protein]] | ||
| + | [[Category: Sulfated lacnac]] | ||
Revision as of 04:02, 12 May 2016
Complex of human Galectin-1 and (3OSO3)Galbeta1-3GlcNAc
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