This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4yjd
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of DAAO(Y228L/R283G) variant (apo form)== | |
| - | + | <StructureSection load='4yjd' size='340' side='right' caption='[[4yjd]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4yjd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YJD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YJD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yjh|4yjh]], [[4yjg|4yjg]], [[4yjf|4yjf]]</td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-amino-acid_oxidase D-amino-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.3 1.4.3.3] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yjd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yjd OCA], [http://pdbe.org/4yjd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yjd RCSB], [http://www.ebi.ac.uk/pdbsum/4yjd PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/OXDA_PIG OXDA_PIG]] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: D-amino-acid oxidase]] | ||
[[Category: Asano, Y]] | [[Category: Asano, Y]] | ||
| + | [[Category: Ishitsubo, E]] | ||
| + | [[Category: Kawahara, N]] | ||
[[Category: Nakano, S]] | [[Category: Nakano, S]] | ||
[[Category: Tokiwa, H]] | [[Category: Tokiwa, H]] | ||
| - | [[Category: | + | [[Category: Yasukawa, K]] |
| - | [[Category: | + | [[Category: Amine oxidase]] |
| + | [[Category: Apo form]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Variant of d-amino acid oxidase]] | ||
Revision as of 04:02, 12 May 2016
Crystal structure of DAAO(Y228L/R283G) variant (apo form)
| |||||||||||
