4s0u
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of NKG2D in complex with ULBP6== | |
| - | + | <StructureSection load='4s0u' size='340' side='right' caption='[[4s0u]], [[Resolution|resolution]] 2.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4s0u]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S0U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s0u OCA], [http://pdbe.org/4s0u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4s0u RCSB], [http://www.ebi.ac.uk/pdbsum/4s0u PDBsum]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[ | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Mohammed, F]] | [[Category: Mohammed, F]] | ||
| + | [[Category: Willcox, B E]] | ||
| + | [[Category: Affinity and autoimmunity]] | ||
| + | [[Category: C-type lectin domain]] | ||
| + | [[Category: Graft versus leukaemia]] | ||
| + | [[Category: Immune system]] | ||
| + | [[Category: Leukaemia]] | ||
| + | [[Category: Nkg2d]] | ||
| + | [[Category: Nkg2dl]] | ||
Revision as of 18:37, 12 May 2016
Crystal structure of NKG2D in complex with ULBP6
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