4xwk
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==P-glycoprotein co-crystallized with BDE-100== | |
| - | + | <StructureSection load='4xwk' size='340' side='right' caption='[[4xwk]], [[Resolution|resolution]] 3.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4xwk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XWK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XWK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4C8:2,4-DIBROMOPHENYL+2,4,6-TRIBROMOPHENYL+ETHER'>4C8</scene></td></tr> | |
| - | [[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xenobiotic-transporting_ATPase Xenobiotic-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.44 3.6.3.44] </span></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xwk OCA], [http://pdbe.org/4xwk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xwk RCSB], [http://www.ebi.ac.uk/pdbsum/4xwk PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Xenobiotic-transporting ATPase]] | ||
[[Category: Chang, G]] | [[Category: Chang, G]] | ||
| + | [[Category: McGrath, A P]] | ||
| + | [[Category: Rees, S D]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Transporter]] | ||
Revision as of 11:57, 13 May 2016
P-glycoprotein co-crystallized with BDE-100
| |||||||||||
