5hyz
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of SCL7 in Oryza sativa== | |
| + | <StructureSection load='5hyz' size='340' side='right' caption='[[5hyz]], [[Resolution|resolution]] 1.82Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5hyz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HYZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HYZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hyz OCA], [http://pdbe.org/5hyz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hyz RCSB], [http://www.ebi.ac.uk/pdbsum/5hyz PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | GRAS proteins belong to a plant-specific protein family with many members and play essential roles in plant growth and development, functioning primarily in transcriptional regulation. Proteins in the family are minimally defined as containing the conserved GRAS domain. Here we have determined the structure of the GRAS domain of Os-SCL7 from Oryza sativa to 1.82A. The structure includes cap and core sub-domains, and elucidates the features of the conserved GRAS LRI, VHIID, LRII, PFYRE, and SAW motifs. The structure is a dimer, with a clear groove to accommodate double-stranded DNA. Docking a DNA segment into the groove to generate an Os-SCL7/DNA complex provides insight into the DNA binding mechanism of GRAS proteins. Furthermore, the in vitro DNA binding property of Os-SCL7 and model-defined recognition residues are assessed by EMSA analysis and mutagenesis assays. These studies reveal the structure and preliminary DNA interaction mechanisms of GRAS proteins and open the door to in-depth investigation and understanding of the individual pathways in which they play important roles. | ||
| - | + | Crystal structure of the GRAS domain of SCARECROW-LIKE 7 in Oryza sativa.,Li S, Zhao Y, Zhao Z, Wu X, Sun L, Liu Q, Wu Y Plant Cell. 2016 Apr 14. pii: tpc.00018.2016. PMID:27081181<ref>PMID:27081181</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| + | <div class="pdbe-citations 5hyz" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Li, S]] | [[Category: Li, S]] | ||
| + | [[Category: Sun, L]] | ||
[[Category: Wu, Y]] | [[Category: Wu, Y]] | ||
[[Category: Zhao, Y]] | [[Category: Zhao, Y]] | ||
| - | [[Category: | + | [[Category: Rossmann fold helix bundle]] |
| + | [[Category: Transcription factor]] | ||
Revision as of 12:07, 13 May 2016
Crystal Structure of SCL7 in Oryza sativa
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