This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4z2a
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of unglycosylated apo human furin @1.89A== | |
| - | + | <StructureSection load='4z2a' size='340' side='right' caption='[[4z2a]], [[Resolution|resolution]] 1.89Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4z2a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z2A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z2A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1p8j|1p8j]], [[4omc|4omc]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Furin Furin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.75 3.4.21.75] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z2a OCA], [http://pdbe.org/4z2a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z2a RCSB], [http://www.ebi.ac.uk/pdbsum/4z2a PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FURIN_HUMAN FURIN_HUMAN]] Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.<ref>PMID:7690548</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Furin]] | ||
| + | [[Category: Gampe, R T]] | ||
[[Category: Pearce, K]] | [[Category: Pearce, K]] | ||
| - | [[Category: Gampe, R.T]] | ||
[[Category: Reid, R]] | [[Category: Reid, R]] | ||
| + | [[Category: Apo]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Serine proteinase]] | ||
| + | [[Category: Unglycosylated]] | ||
Revision as of 19:32, 13 May 2016
Crystal structure of unglycosylated apo human furin @1.89A
| |||||||||||
Categories: Furin | Gampe, R T | Pearce, K | Reid, R | Apo | Hydrolase | Serine proteinase | Unglycosylated
