4z2a

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'''Unreleased structure'''
 
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The entry 4z2a is ON HOLD until Paper Publication
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==Crystal structure of unglycosylated apo human furin @1.89A==
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<StructureSection load='4z2a' size='340' side='right' caption='[[4z2a]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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Authors: Gampe, R.T., Pearce, K., Reid, R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4z2a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z2A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z2A FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1p8j|1p8j]], [[4omc|4omc]]</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Furin Furin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.75 3.4.21.75] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z2a OCA], [http://pdbe.org/4z2a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z2a RCSB], [http://www.ebi.ac.uk/pdbsum/4z2a PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FURIN_HUMAN FURIN_HUMAN]] Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.<ref>PMID:7690548</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Furin]]
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[[Category: Gampe, R T]]
[[Category: Pearce, K]]
[[Category: Pearce, K]]
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[[Category: Gampe, R.T]]
 
[[Category: Reid, R]]
[[Category: Reid, R]]
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[[Category: Apo]]
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[[Category: Hydrolase]]
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[[Category: Serine proteinase]]
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[[Category: Unglycosylated]]

Revision as of 19:32, 13 May 2016

Crystal structure of unglycosylated apo human furin @1.89A

4z2a, resolution 1.89Å

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