This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4zt2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 4zt2 is ON HOLD until Paper Publication
+
==Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-(3,5-dichlorobenzyl)-N'-(1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1575)==
-
 
+
<StructureSection load='4zt2' size='340' side='right' caption='[[4zt2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-
Authors: Koh, C.-Y., Hol, W.G.J.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4zt2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZT2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZT2 FirstGlance]. <br>
-
Description: Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-(3,5-dichlorobenzyl)-N'-(1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1575)
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4RP:N-(3,5-DICHLOROBENZYL)-N-(1H-IMIDAZO[4,5-B]PYRIDIN-2-YL)PROPANE-1,3-DIAMINE'>4RP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
-
[[Category: Hol, W.G.J]]
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zt6|4zt6]], [[4zt5|4zt5]], [[4zt4|4zt4]], [[4zt3|4zt3]], [[4zt7|4zt7]]</td></tr>
-
[[Category: Koh, C.-Y]]
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zt2 OCA], [http://pdbe.org/4zt2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zt2 RCSB], [http://www.ebi.ac.uk/pdbsum/4zt2 PDBsum]</span></td></tr>
 +
</table>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Methionine--tRNA ligase]]
 +
[[Category: Hol, W G.J]]
 +
[[Category: Koh, C Y]]
 +
[[Category: Aar]]
 +
[[Category: Aminoacyl-trna synthetase]]
 +
[[Category: Ligase]]
 +
[[Category: Ligase-ligase inhibitor complex]]
 +
[[Category: Metr]]
 +
[[Category: Protein-inhibitor complex]]
 +
[[Category: Trypanosoma brucei]]

Revision as of 19:34, 13 May 2016

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-(3,5-dichlorobenzyl)-N'-(1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1575)

4zt2, resolution 2.70Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools