Nitroreductase

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{{STRUCTURE_1f5v| PDB=1f5v | SIZE=400| SCENE= |right|CAPTION=E. coli nitroreductase dimer containing FMN, [[1f5v]] }}
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<StructureSection load='1icr' size='350' side='right' caption='E. coli nitroreductase dimer containing FMN and nicotinic acid (PDB entry [[1icr]])' scene=''>
== Function ==
== Function ==
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The NR is of special interest due to its potential use as activator of prodrugs in cancer therapy.
The NR is of special interest due to its potential use as activator of prodrugs in cancer therapy.
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== Structural highlights ==
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</StructureSection>
==3D structures of nitroreductase==
==3D structures of nitroreductase==

Revision as of 10:04, 15 May 2016

E. coli nitroreductase dimer containing FMN and nicotinic acid (PDB entry 1icr)

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3D structures of nitroreductase

Updated on 15-May-2016

References

  1. Lovering AL, Hyde EI, Searle PF, White SA. The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution. J Mol Biol. 2001 May 25;309(1):203-13. PMID:11491290 doi:10.1006/jmbi.2001.4653

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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