4zof
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Lobenzarit-like inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)== | |
| - | + | <StructureSection load='4zof' size='340' side='right' caption='[[4zof]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4zof]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZOF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZOF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=59L:2-[(2-CARBOXY-5-NITROPHENYL)AMINO]-3-METHYLBENZOIC+ACID'>59L</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4giu|4giu]], [[3qr9|3qr9]], [[4zoj|4zoj]], [[4zok|4zok]]</td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr> |
| - | [[Category: Evans, G | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zof OCA], [http://pdbe.org/4zof PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zof RCSB], [http://www.ebi.ac.uk/pdbsum/4zof PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Anthranilate phosphoribosyltransferase]] | ||
| + | [[Category: Baker, E N]] | ||
| + | [[Category: Evans, G L]] | ||
| + | [[Category: Lott, J S]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Lobenzarit-like analogue]] | ||
| + | [[Category: Magnesium binding]] | ||
| + | [[Category: Phosphoribosylpyrophosphate]] | ||
| + | [[Category: Phosphoribosyltransferase]] | ||
| + | [[Category: Prpp]] | ||
| + | [[Category: Tbsgc]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 17:03, 15 May 2016
Lobenzarit-like inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
| |||||||||||
