4zok
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Methylsulfonyl-containing inhibitor bound in the substrate capture site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)== | |
| - | + | <StructureSection load='4zok' size='340' side='right' caption='[[4zok]], [[Resolution|resolution]] 2.34Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4zok]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZOK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZOK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=62L:4-METHYL-2-{[2-METHYL-6-(METHYLSULFONYL)PHENYL]AMINO}BENZOIC+ACID'>62L</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4giu|4giu]], [[3qr9|3qr9]], [[4zof|4zof]], [[4zoj|4zoj]]</td></tr> |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr> |
| - | [[Category: Evans, G | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zok OCA], [http://pdbe.org/4zok PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zok RCSB], [http://www.ebi.ac.uk/pdbsum/4zok PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Anthranilate phosphoribosyltransferase]] | ||
| + | [[Category: Baker, E N]] | ||
| + | [[Category: Evans, G L]] | ||
| + | [[Category: Lott, J S]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Lobenzarit-like analogue]] | ||
| + | [[Category: Magnesium binding]] | ||
| + | [[Category: Phosphoribosylpyrophosphate]] | ||
| + | [[Category: Phosphoribosyltransferase]] | ||
| + | [[Category: Prpp]] | ||
| + | [[Category: Tbsgc]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 17:03, 15 May 2016
Methylsulfonyl-containing inhibitor bound in the substrate capture site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
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