5iv7
From Proteopedia
(Difference between revisions)
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- | ''' | + | {{Large structure}} |
- | + | ==Cryo-electron microscopy structure of the star-shaped, hubless post-attachment T4 baseplate== | |
- | + | <StructureSection load='5iv7' size='340' side='right' caption='[[5iv7]], [[Resolution|resolution]] 6.77Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5iv7]] is a 96 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IV7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IV7 FirstGlance]. <br> | |
- | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iv7 OCA], [http://pdbe.org/5iv7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iv7 RCSB], [http://www.ebi.ac.uk/pdbsum/5iv7 PDBsum]</span></td></tr> | |
- | + | </table> | |
- | [[Category: | + | {{Large structure}} |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/BP11_BPT4 BP11_BPT4]] Baseplate protein that is part of the baseplate wedge and that connects the short tail fibers to the baseplate (PubMed:15315755). Involved in the tail assembly.<ref>PMID:15315755</ref> <ref>PMID:21129200</ref> [[http://www.uniprot.org/uniprot/BP08_BPT4 BP08_BPT4]] Baseplate protein that is part of the baseplate wedge. Involved in the tail assembly.<ref>PMID:15315755</ref> <ref>PMID:21129200</ref> [[http://www.uniprot.org/uniprot/BP25_BPT4 BP25_BPT4]] Baseplate protein that is part of the outer wedges of the baseplate (PubMed:15315755). Probably plays a role as a connector between the central and peripheral parts of the baseplate. Involved in the tail assembly.[UniProtKB:P51768]<ref>PMID:15315755</ref> <ref>PMID:21129200</ref> [[http://www.uniprot.org/uniprot/BP07_BPT4 BP07_BPT4]] Baseplate protein that is part of the baseplate wedge. Involved in the tail assembly.<ref>PMID:2254933</ref> <ref>PMID:21129200</ref> [[http://www.uniprot.org/uniprot/BP53_BPT4 BP53_BPT4]] Baseplate protein that is part of the baseplate wedge (PubMed:15315755). Involved in the tail assembly.<ref>PMID:15315755</ref> <ref>PMID:21129200</ref> [[http://www.uniprot.org/uniprot/BP06_BPT4 BP06_BPT4]] Baseplate protein that is part of the baseplate wedge (PubMed:15315755). Involved in the tail assembly.<ref>PMID:15315755</ref> <ref>PMID:21129200</ref> [[http://www.uniprot.org/uniprot/BP09_BPT4 BP09_BPT4]] Baseplate protein that connects the long tail fibers to the baseplate and probably triggers the tail contraction after virus attachment to a host cell (PubMed:10545330). Involved in the tail assembly (PubMed:21129200).<ref>PMID:10545330</ref> <ref>PMID:21129200</ref> [[http://www.uniprot.org/uniprot/BP10_BPT4 BP10_BPT4]] Baseplate protein that is part of the baseplate wedge and that connects the short tail fibers to the baseplate (PubMed:16554069). During infection, the baseplate undergoes a conformational change from a dome-shaped to a star-shaped structure. At this point, gp10 rotates and acts as a lever that unfolds the short tail fibers, which then interact with host cell surface receptors. Involved in the tail assembly.<ref>PMID:16554069</ref> <ref>PMID:21129200</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Enterobacteria phage t4]] | ||
+ | [[Category: Goldie, K N]] | ||
+ | [[Category: Guerrero-Ferreira, R C]] | ||
+ | [[Category: Leiman, P G]] | ||
+ | [[Category: Stahlberg, H]] | ||
+ | [[Category: Taylor, N M.I]] | ||
+ | [[Category: Bacterial virus]] | ||
+ | [[Category: Bacteriophage]] | ||
+ | [[Category: Baseplate]] | ||
+ | [[Category: Cell attachment]] | ||
+ | [[Category: Hubless]] | ||
+ | [[Category: Infection]] | ||
+ | [[Category: Membrane-piercing]] | ||
+ | [[Category: Post-attachment]] | ||
+ | [[Category: Star-shaped]] | ||
+ | [[Category: T4]] | ||
+ | [[Category: Viral protein]] |
Revision as of 08:35, 1 June 2016
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Cryo-electron microscopy structure of the star-shaped, hubless post-attachment T4 baseplate
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