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5bow
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==CRYSTAL STRUCTURE OF IL-38== | |
| - | + | <StructureSection load='5bow' size='340' side='right' caption='[[5bow]], [[Resolution|resolution]] 1.31Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5bow]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BOW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BOW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ize|4ize]], [[1md6|1md6]], [[1ilr|1ilr]]</td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bow OCA], [http://pdbe.org/5bow PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bow RCSB], [http://www.ebi.ac.uk/pdbsum/5bow PDBsum]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IL1FA_HUMAN IL1FA_HUMAN]] Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.<ref>PMID:22315422</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Guenther, S]] | [[Category: Guenther, S]] | ||
| + | [[Category: Sundberg, E J]] | ||
| + | [[Category: Beta trefoil]] | ||
| + | [[Category: Innate immune signaling]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 06:05, 2 June 2016
CRYSTAL STRUCTURE OF IL-38
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