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O-GlcNAc transferase
From Proteopedia
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**[[2gak]] – mOGT – mouse | **[[2gak]] – mOGT – mouse | ||
| - | **[[2j0a]], [[3otk]] – mOGT catalytic domain (mutant) | + | **[[2j0a]], [[3otk]] – mOGT catalytic domain (mutant)<br /> |
| + | **[[5a01]] - DmOGT TPR and catalytic domains – ''Drosophila melanogaster''<br /> | ||
| + | **[[5djs]] - OGT TPR and catalytic domains (mutant) – ''Thermobaculum terrenum''<br /> | ||
| + | |||
*O-GlcNAc transferase binary complexes | *O-GlcNAc transferase binary complexes | ||
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**[[2xgm]] – XcOGT + alloxan + mesoxalylurea | **[[2xgm]] – XcOGT + alloxan + mesoxalylurea | ||
| - | **[[ | + | **[[2xgo]] - XcOGT + UDP-GlcNAc |
**[[2xgs]] - XcOGT + UDP | **[[2xgs]] - XcOGT + UDP | ||
| - | **[[1nlm]] – OGT + UDP-acetylglucosamine – ''Escherichia coli'' | + | **[[1nlm]] – OGT + UDP-acetylglucosamine – ''Escherichia coli''<br /> |
| + | **[[4cdr]] - hOGT TPR and catalytic domains + UDP-peptide conjugate<br /> | ||
| + | **[[5bnw]], [[3tax]] - hOGT TPR and catalytic domains + substrate peptide <br /> | ||
| + | **[[4gz5]], [[4gz6]] - hOGT TPR and catalytic domains + UDP-GlcNAc<br /> | ||
| + | |||
| + | *OGT higher complexes | ||
| + | **[[2xgm]] – XcOGT + alloxan + mesoxalylurea<br /> | ||
**[[3ee5]] – hOGT + UDP + NAG + galactose + naphthalene derivative<br /> | **[[3ee5]] – hOGT + UDP + NAG + galactose + naphthalene derivative<br /> | ||
**[[4ay5]], [[4gyw]], [[4gyy]], [[4gz3]] - hOGT TPR and catalytic domains + UDP + NAG + glycopeptide<br /> | **[[4ay5]], [[4gyw]], [[4gyy]], [[4gz3]] - hOGT TPR and catalytic domains + UDP + NAG + glycopeptide<br /> | ||
| - | **[[4cdr]] - hOGT TPR and catalytic domains + UDP-peptide conjugate<br /> | ||
| - | **[[4gz5]], [[4gz6]] - hOGT TPR and catalytic domains + UDP-GlcNAc<br /> | ||
**[[4n39]], [[4n3a]], [[4n3b]], [[4n3c]] - hOGT TPR and catalytic domains + UDP + host cell factor peptide<br /> | **[[4n39]], [[4n3a]], [[4n3b]], [[4n3c]] - hOGT TPR and catalytic domains + UDP + host cell factor peptide<br /> | ||
| + | **[[4xi9]], [[4xif]], [[5c1d]], [[4ay6]] - hOGT TPR and catalytic domains + UDP-GlcNac + substrate peptide<br /> | ||
| + | **[[4pqg]] - OGT TPR and catalytic domains + UDP + GlcNac – Streptococcus pneumoniae<br /> | ||
| + | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:30, 7 June 2016
O-GlcNac transferase (OGT) catalyzes the addition of N-acetylglucosamine (GlcNAc) to serine or threonine residues by O-glycosylation. OGT contains 2 subunits: a 110 kDa and a 78kDa. The 110 kDa subunit contains a superhelical domain with 13 tetratricopeptide (TPR) repeats. The TPR motif consists of 34 amino acids and mediates protein-protein interactions. For details see Human O-GlcNAc transferase.
3D structures of O-GlcNAc transferase
Updated on 07-June-2016
