Pantothenate synthetase
From Proteopedia
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| - | + | <StructureSection load='1n2e' size='350' side='right' caption='Pantothenate synthetase complex with pantoate, AMPPNP (stick model), sulfate, Mg+2 ion (green), ethanol and glycerol (PDB entry [[1n2e]])' scene=''> | |
| - | <StructureSection load=' | + | |
== Function == | == Function == | ||
'''Pantothenate synthetase''' (PS) catalyzes the ATP-dependent condensation of pantoate and β-alanine to form pantothenate. | '''Pantothenate synthetase''' (PS) catalyzes the ATP-dependent condensation of pantoate and β-alanine to form pantothenate. | ||
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== Relevance == | == Relevance == | ||
Pantothenate (vitamin B5) biosynthesis is essential for the virulence of ''Mycobacterium tuberculosis'' thus its blockage can be used as a potential drug target. | Pantothenate (vitamin B5) biosynthesis is essential for the virulence of ''Mycobacterium tuberculosis'' thus its blockage can be used as a potential drug target. | ||
| + | == Structural highlights == | ||
| + | </StructureSection> | ||
==3D structures of pantothenate synthetase== | ==3D structures of pantothenate synthetase== | ||
Revision as of 10:28, 14 June 2016
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3D structures of pantothenate synthetase
Updated on 14-June-2016
