Parvalbumin
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='2pvb' size='350' side='right' caption='Pike parvalbumin complex with Ca+2 ions (green), ammonium, acetyl and formate (PDB entry [[2pvb]])' scene=''> | + | <StructureSection load='2pvb' size='350' side='right' caption='Pike parvalbumin complex with Ca+2 ions (green), ammonium ion (blue), acetyl and formate (PDB entry [[2pvb]])' scene=''> |
== Function == | == Function == | ||
| - | '''Parvalbumin (PVA)''' is a calcium-binding albumin protein. PVA is involved in calcium signaling<ref>PMID:11867433</ref>. PVA contains 3 domains: AB, CD (N-terminal) and EF (C-terminal). <br /> | + | '''Parvalbumin (PVA)''' is a calcium-binding albumin protein. PVA is involved in calcium signaling<ref>PMID:11867433</ref>. PVA contains 3 domains each containing 2 helices: AB, CD (N-terminal) and EF (C-terminal). <br /> |
See also<br /> | See also<br /> | ||
* [[EF hand]] | * [[EF hand]] | ||
Revision as of 08:37, 15 June 2016
| |||||||||||
3D Structures of Parvalbumin
Updated on 15-June-2016
References
- ↑ Cates MS, Teodoro ML, Phillips GN Jr. Molecular mechanisms of calcium and magnesium binding to parvalbumin. Biophys J. 2002 Mar;82(3):1133-46. PMID:11867433 doi:http://dx.doi.org/10.1016/S0006-3495(02)75472-6
- ↑ Lim DL, Neo KH, Yi FC, Chua KY, Goh DL, Shek LP, Giam YC, Van Bever HP, Lee BW. Parvalbumin--the major tropical fish allergen. Pediatr Allergy Immunol. 2008 Aug;19(5):399-407. doi:, 10.1111/j.1399-3038.2007.00674.x. Epub 2008 Jan 25. PMID:18221468 doi:http://dx.doi.org/10.1111/j.1399-3038.2007.00674.x
- ↑ Declercq JP, Evrard C, Lamzin V, Parello J. Crystal structure of the EF-hand parvalbumin at atomic resolution (0.91 A) and at low temperature (100 K). Evidence for conformational multistates within the hydrophobic core. Protein Sci. 1999 Oct;8(10):2194-204. PMID:10548066
