5i84
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the Xanthomonas citri phosphate-binding protein PhoX== | |
| + | <StructureSection load='5i84' size='340' side='right' caption='[[5i84]], [[Resolution|resolution]] 2.98Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5i84]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I84 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I84 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i84 OCA], [http://pdbe.org/5i84 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i84 RCSB], [http://www.ebi.ac.uk/pdbsum/5i84 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q8PM55_XANAC Q8PM55_XANAC]] Part of the ABC transporter complex PstSACB involved in phosphate import.[PIRNR:PIRNR002756] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Xanthomonas axonopodis pv. citri (X. citri) is an important bacterium that causes citrus canker disease in plants in Brazil and around the world, leading to significant economic losses. Determination of the physiology and mechanisms of pathogenesis of this bacterium is an important step in the development of strategies for its containment. Phosphate is an essential ion in all microrganisms owing its importance during the synthesis of macromolecules and in gene and protein regulation. Interestingly, X. citri has been identified to present two periplasmic binding proteins that have not been further characterized: PstS, from an ATP-binding cassette for high-affinity uptake and transport of phosphate, and PhoX, which is encoded by an operon that also contains a putative porin for the transport of phosphate. Here, the expression, purification and crystallization of the phosphate-binding protein PhoX and X-ray data collection at 3.0 A resolution are described. Biochemical, biophysical and structural data for this protein will be helpful in the elucidation of its function in phosphate uptake and the physiology of the bacterium. | ||
| - | + | Crystallization and preliminary X-ray diffraction analysis of the phosphate-binding protein PhoX from Xanthomonas citri.,Pegos VR, Medrano FJ, Balan A Acta Crystallogr F Struct Biol Commun. 2014 Dec 1;70(Pt 12):1604-7. doi:, 10.1107/S2053230X14021840. Epub 2014 Nov 14. PMID:25484207<ref>PMID:25484207</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 5i84" style="background-color:#fffaf0;"></div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Balan, A]] | [[Category: Balan, A]] | ||
| - | [[Category: Medrano, F | + | [[Category: Medrano, F J]] |
| + | [[Category: Pegos, V R]] | ||
| + | [[Category: Abc transporter]] | ||
| + | [[Category: Periplasmic-binding protein]] | ||
| + | [[Category: Phosphate-binding protein]] | ||
| + | [[Category: Phox]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 15:14, 20 June 2016
Structure of the Xanthomonas citri phosphate-binding protein PhoX
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