5fo5

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'''Unreleased structure'''
 
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The entry 5fo5 is ON HOLD until Paper Publication
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==Structure of the DNA-binding domain of Escherichia coli methionine biosynthesis regulator MetR==
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<StructureSection load='5fo5' size='340' side='right' caption='[[5fo5]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
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Authors: Punekar, A.S., Porter, J., Urbanowski, M.L., Stauffer, G.V., Carr, S.B., Phillips, S.E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5fo5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FO5 FirstGlance]. <br>
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Description: Structure of the DNA-binding domain of Escherichia coli methionine biosynthesis regulator MetR
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fo5 OCA], [http://pdbe.org/5fo5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fo5 RCSB], [http://www.ebi.ac.uk/pdbsum/5fo5 PDBsum]</span></td></tr>
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[[Category: Urbanowski, M.L]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/METR_ECOLI METR_ECOLI]] Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes. MetR is also a negative regulator of its own expression. Binds homocysteine as an inducer.
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__TOC__
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</StructureSection>
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[[Category: Carr, S B]]
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[[Category: Phillips, S E]]
[[Category: Porter, J]]
[[Category: Porter, J]]
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[[Category: Punekar, A.S]]
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[[Category: Punekar, A S]]
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[[Category: Phillips, S.E]]
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[[Category: Stauffer, G V]]
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[[Category: Stauffer, G.V]]
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[[Category: Urbanowski, M L]]
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[[Category: Carr, S.B]]
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[[Category: Activator]]
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[[Category: Dna-binding]]
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[[Category: Hth]]
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[[Category: Lysr-type transcriptional regulator]]
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[[Category: Methionine biosynthesis]]
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[[Category: Repressor]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]

Revision as of 15:23, 20 June 2016

Structure of the DNA-binding domain of Escherichia coli methionine biosynthesis regulator MetR

5fo5, resolution 2.16Å

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