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5l3s
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the GTPase heterodimer of crenarchaeal SRP54 and FtsY== | |
| - | + | <StructureSection load='5l3s' size='340' side='right' caption='[[5l3s]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5l3s]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L3S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L3S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l3s OCA], [http://pdbe.org/5l3s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l3s RCSB], [http://www.ebi.ac.uk/pdbsum/5l3s PDBsum]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SRP54_SULSO SRP54_SULSO]] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (By similarity). [[http://www.uniprot.org/uniprot/FTSY_SULAC FTSY_SULAC]] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).[HAMAP-Rule:MF_00920] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Bange, G]] | [[Category: Bange, G]] | ||
| + | [[Category: Sinning, I]] | ||
[[Category: Wild, K]] | [[Category: Wild, K]] | ||
| - | [[Category: | + | [[Category: Co-translational protein targeting]] |
| + | [[Category: Gtpase]] | ||
| + | [[Category: Protein transport]] | ||
| + | [[Category: Signal recognition particle]] | ||
Revision as of 15:29, 20 June 2016
Structure of the GTPase heterodimer of crenarchaeal SRP54 and FtsY
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