5f4t
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the human sperm Izumo1 residues 22-254== | |
| - | + | <StructureSection load='5f4t' size='340' side='right' caption='[[5f4t]], [[Resolution|resolution]] 3.08Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5f4t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F4T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f4e|5f4e]], [[5f4q|5f4q]], [[5f4v|5f4v]]</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f4t OCA], [http://pdbe.org/5f4t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f4t RCSB], [http://www.ebi.ac.uk/pdbsum/5f4t PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/IZUM1_HUMAN IZUM1_HUMAN]] Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'.<ref>PMID:15759005</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aydin, H]] | ||
| + | [[Category: Lee, J E]] | ||
[[Category: Sultana, A]] | [[Category: Sultana, A]] | ||
| - | [[Category: | + | [[Category: Adhesion]] |
| - | [[Category: | + | [[Category: Cell adhesion]] |
| + | [[Category: Cysteine-rich]] | ||
| + | [[Category: Fusion]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Membrane-bound]] | ||
Revision as of 22:25, 20 June 2016
Crystal structure of the human sperm Izumo1 residues 22-254
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Categories: Aydin, H | Lee, J E | Sultana, A | Adhesion | Cell adhesion | Cysteine-rich | Fusion | Glycoprotein | Membrane-bound
