5jlh
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution== | |
| - | + | <StructureSection load='5jlh' size='340' side='right' caption='[[5jlh]], [[Resolution|resolution]] 3.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5jlh]] is a 11 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JLH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr> |
| - | [[Category: Heissler, S | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jlh OCA], [http://pdbe.org/5jlh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jlh RCSB], [http://www.ebi.ac.uk/pdbsum/5jlh PDBsum]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/ACTG_HUMAN ACTG_HUMAN]] Baraitser-Winter syndrome;Autosomal dominant non-syndromic sensorineural deafness type DFNA. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. [[http://www.uniprot.org/uniprot/MYH14_HUMAN MYH14_HUMAN]] Peripheral neuropathy-myopathy-hoarseness-hearing loss syndrome;Autosomal dominant non-syndromic sensorineural deafness type DFNA. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ACTG_HUMAN ACTG_HUMAN]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [[http://www.uniprot.org/uniprot/MYH14_HUMAN MYH14_HUMAN]] Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ecken, J von der]] | ||
| + | [[Category: Heissler, S M]] | ||
| + | [[Category: Manstein, D J]] | ||
[[Category: Pathan-Chhatbar, S]] | [[Category: Pathan-Chhatbar, S]] | ||
| - | [[Category: Manstein, D.J]] | ||
[[Category: Raunser, S]] | [[Category: Raunser, S]] | ||
| + | [[Category: Contractile filament]] | ||
| + | [[Category: Contractile protein]] | ||
| + | [[Category: Cryo em]] | ||
| + | [[Category: Cytoskeleton]] | ||
| + | [[Category: F-actin]] | ||
| + | [[Category: Filament]] | ||
| + | [[Category: Hydrolase complex]] | ||
| + | [[Category: Muscle]] | ||
| + | [[Category: Myosin]] | ||
| + | [[Category: Protein polymer]] | ||
| + | [[Category: Structural protein]] | ||
| + | [[Category: Thin filament]] | ||
| + | [[Category: Tropomyosin]] | ||
Revision as of 22:27, 20 June 2016
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
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