Pertussis toxin

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'''Pertussis toxin''' (PT) is produced by the bacterium ''Bordetella pertussis'' and is the cause of whooping cough. For additional details see [[Pertussis Toxin-ATP Complex]].<br />
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'''Pertussis toxin''' (PT) is produced by the bacterium ''Bordetella pertussis'' and is the cause of whooping cough<ref>PMID:15845471</ref>. For additional details see [[Pertussis Toxin-ATP Complex]].<br />
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Pertactin is another toxin produced by ''Bordetella''. For details see [[P.69 Pertactin Structure and Function]].
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'''Pertactin''' is another toxin produced by ''Bordetella''. For details see [[P.69 Pertactin Structure and Function]].
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[[1dab]] - BpPer<br />
[[1dab]] - BpPer<br />
[[2iou]] - Per extracellular domain + major tropism determinant - ''Bordetella bronchiseptica''<br />
[[2iou]] - Per extracellular domain + major tropism determinant - ''Bordetella bronchiseptica''<br />
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:45, 22 June 2016

Template:STRUCTURE 1prt


Pertussis toxin (PT) is produced by the bacterium Bordetella pertussis and is the cause of whooping cough[1]. For additional details see Pertussis Toxin-ATP Complex.
Pertactin is another toxin produced by Bordetella. For details see P.69 Pertactin Structure and Function.


3D Structures of Pertussis toxin

1prt – BpPT - Bordetella pertussis
1pto – BpPT + galactose
1bcp – BpPT + ATP

Pertactin

1dab - BpPer
2iou - Per extracellular domain + major tropism determinant - Bordetella bronchiseptica

References

  1. Carbonetti NH, Artamonova GV, Andreasen C, Bushar N. Pertussis toxin and adenylate cyclase toxin provide a one-two punch for establishment of Bordetella pertussis infection of the respiratory tract. Infect Immun. 2005 May;73(5):2698-703. PMID:15845471 doi:http://dx.doi.org/10.1128/IAI.73.5.2698-2703.2005

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Michal Harel, Jonathan Tringali

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