5fx8

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'''Unreleased structure'''
 
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The entry 5fx8 is ON HOLD until Paper Publication
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==Complete structure of manganese lipoxygenase of Gaeumannomyces graminis and partial structure of zonadhesin of Komagataella pastoris==
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<StructureSection load='5fx8' size='340' side='right' caption='[[5fx8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors: Chen, Y., Wennman, A., Karkehanadi, S., Engstrom, A., Oliw, E.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5fx8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Komagataella_phaffii Komagataella phaffii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FX8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FX8 FirstGlance]. <br>
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Description: Complete structure of manganese lipoxygenase of Gaeumannomyces graminis and partial structure of zonadhesin of Komagataella pastoris
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.12 1.13.11.12] </span></td></tr>
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[[Category: Oliw, E.H]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fx8 OCA], [http://pdbe.org/5fx8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fx8 RCSB], [http://www.ebi.ac.uk/pdbsum/5fx8 PDBsum]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MNLOX_GAEGA MNLOX_GAEGA]] Lipoxygenase that metabolizes linoleic and alpha-linolenic acids to 11S- and 13R-hydroperoxy fatty acids. At the end of lipoxygenation, the intermediate product 11S-HPODE from linoleic acid is then transformed into 13R-HPODE as the final product. It also acts on alpha-linolenic acid producing 11S-HPOTrE and 13R-HPOTrE with subsequent transformation of 11S-HPOTrE to 13R-HPOTrE as final product.<ref>PMID:15629124</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Komagataella phaffii]]
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[[Category: Oxidoreductase]]
[[Category: Chen, Y]]
[[Category: Chen, Y]]
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[[Category: Engstrom, A]]
[[Category: Karkehanadi, S]]
[[Category: Karkehanadi, S]]
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[[Category: Engstrom, A]]
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[[Category: Oliw, E H]]
[[Category: Wennman, A]]
[[Category: Wennman, A]]
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[[Category: Chian a and b]]
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[[Category: Fattty acid oxygenation]]
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[[Category: Fungal adhesion protein n-terminal domain]]
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[[Category: Linoleate 11s-and 13r- lipoxygenase]]
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[[Category: Manganese. chain u]]

Revision as of 23:27, 23 June 2016

Complete structure of manganese lipoxygenase of Gaeumannomyces graminis and partial structure of zonadhesin of Komagataella pastoris

5fx8, resolution 2.60Å

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