1jgs
From Proteopedia
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|PDB= 1jgs |SIZE=350|CAPTION= <scene name='initialview01'>1jgs</scene>, resolution 2.3Å | |PDB= 1jgs |SIZE=350|CAPTION= <scene name='initialview01'>1jgs</scene>, resolution 2.3Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=SAL:2-HYDROXYBENZOIC ACID'>SAL</scene> | + | |LIGAND= <scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [http://www.ebi.ac.uk/pdbsum/1jgs PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB]</span> | ||
}} | }} | ||
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[[Category: Mealy, T R.]] | [[Category: Mealy, T R.]] | ||
[[Category: Seaton, B A.]] | [[Category: Seaton, B A.]] | ||
| - | [[Category: SAL]] | ||
[[Category: antibiotic resistance]] | [[Category: antibiotic resistance]] | ||
[[Category: dna-binding]] | [[Category: dna-binding]] | ||
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[[Category: transcription regulation]] | [[Category: transcription regulation]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:33:25 2008'' |
Revision as of 18:33, 30 March 2008
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| , resolution 2.3Å | |||||||
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| Ligands: | |||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Multiple Antibiotic Resistance Repressor, MarR
Overview
MarR is a regulator of multiple antibiotic resistance in Escherichia coli. It is the prototypical member of the MarR family of regulatory proteins found in bacteria and archaea that play important roles in the development of antibiotic resistance, a global health problem. Here we describe the crystal structure of the MarR protein, determined at a resolution of 2.3 A. This is the first reported crystal structure of a member of this newly-described protein family. The structure shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.
About this Structure
1JGS is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution., Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF, Nat Struct Biol. 2001 Aug;8(8):710-4. PMID:11473263
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