Phosphoglucose isomerase

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{{STRUCTURE_1hox| PDB=1hox | SIZE=400| SCENE= |right|CAPTION=Rabbit phosphoglucose isomerase dimer complex with fructose-6-phosphate, [[1hox]] }}
{{STRUCTURE_1hox| PDB=1hox | SIZE=400| SCENE= |right|CAPTION=Rabbit phosphoglucose isomerase dimer complex with fructose-6-phosphate, [[1hox]] }}
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== Function ==
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'''Phosphoglucose isomerase''' (PGI) catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate<ref>PMID:25811607</ref>. PGI is part of the glycolysis cycle. For more details see [[Phosphoglucoisomerase]].
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'''Phosphoglucose isomerase''' (PGI) catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate. PGI is part of the glycolysis cycle. For more details see [[Phosphoglucoisomerase]].
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== Disease ==
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Increased expression of PGI enhances colorectal cancer metastasis<ref>PMID:19787266</ref>.
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== Structural highlights ==
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</StructureSection>
== 3D Structures of phosphoglucose isomerase ==
== 3D Structures of phosphoglucose isomerase ==
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**[[1iri]] – hPGI + erythrose-4-phosphate<br />
**[[1iri]] – hPGI + erythrose-4-phosphate<br />
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:26, 27 June 2016

Template:STRUCTURE 1hox

Contents

Function

Phosphoglucose isomerase (PGI) catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate[1]. PGI is part of the glycolysis cycle. For more details see Phosphoglucoisomerase.

Disease

Increased expression of PGI enhances colorectal cancer metastasis[2].

Structural highlights

</StructureSection>

3D Structures of phosphoglucose isomerase

Updated on 27-June-2016

References

  1. ↑ Bahaji A, Sanchez-Lopez AM, De Diego N, Munoz FJ, Baroja-Fernandez E, Li J, Ricarte-Bermejo A, Baslam M, Aranjuelo I, Almagro G, Humplik JF, Novak O, Spichal L, Dolezal K, Pozueta-Romero J. Plastidic phosphoglucose isomerase is an important determinant of starch accumulation in mesophyll cells, growth, photosynthetic capacity, and biosynthesis of plastidic cytokinins in Arabidopsis. PLoS One. 2015 Mar 26;10(3):e0119641. doi: 10.1371/journal.pone.0119641., eCollection 2015. PMID:25811607 doi:http://dx.doi.org/10.1371/journal.pone.0119641
  2. ↑ Tsutsumi S, Fukasawa T, Yamauchi H, Kato T, Kigure W, Morita H, Asao T, Kuwano H. Phosphoglucose isomerase enhances colorectal cancer metastasis. Int J Oncol. 2009 Nov;35(5):1117-21. PMID:19787266

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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