Plasminogen activator inhibitor
From Proteopedia
(Difference between revisions)
| Line 2: | Line 2: | ||
'''Plasminogen activator inhibitor''' (PAI) is a serine protease inhibitor.<br /> | '''Plasminogen activator inhibitor''' (PAI) is a serine protease inhibitor.<br /> | ||
| - | * '''PAI-1''' inhibits tissue plasminogen activator and urokinase.<br /> | + | * '''PAI-1''' inhibits tissue plasminogen activator and urokinase<ref>PMID:15634264</ref>.<br /> |
* '''PAI-2''' is secreted by the placenta and is present during pregnancy.<br /> | * '''PAI-2''' is secreted by the placenta and is present during pregnancy.<br /> | ||
* '''PAI-3''' inhibits enzymes in blood coagulation. | * '''PAI-3''' inhibits enzymes in blood coagulation. | ||
| Line 37: | Line 37: | ||
**[[1lq8]], [[3dy0]] – hPAI-3 cleaved | **[[1lq8]], [[3dy0]] – hPAI-3 cleaved | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 06:54, 5 July 2016
Plasminogen activator inhibitor (PAI) is a serine protease inhibitor.
- PAI-1 inhibits tissue plasminogen activator and urokinase[1].
- PAI-2 is secreted by the placenta and is present during pregnancy.
- PAI-3 inhibits enzymes in blood coagulation.
3D Structures of plasminogen activator inhibitor
Updated on 05-July-2016
References
- ↑ Lijnen HR. Pleiotropic functions of plasminogen activator inhibitor-1. J Thromb Haemost. 2005 Jan;3(1):35-45. PMID:15634264 doi:http://dx.doi.org/10.1111/j.1538-7836.2004.00827.x
