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Plectin
From Proteopedia
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| - | <Structure load='1sh6' size='400' caption='Mouse plectin actin-binding domain [[1sh6]]' scene= ' | + | <Structure load='1sh6' size='400' caption='Mouse plectin actin-binding domain [[1sh6]]' scene= '> |
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| - | '''Plectin''', a universal and functionally versatile cytolinker protein, can be divided in three main sections; a central coiled-coil rod domain, N and C-terminal globular region and exhibits a dumbbell like structure <ref>PMID:3430617</ref>. C-terminal region is composed of 6 homologous repeating domains, and this region has a role in binding to intermediate filaments such as vimentin and cytokeratin (2). N-terminal globular region contains actin binding domain (ABD) comprising two calponin homology (CH) domains and N-terminal arm, which varies among isoforms (3). For more details see [[Group:MUZIC:Plectin]]. | + | '''Plectin''', a universal and functionally versatile cytolinker protein, can be divided in three main sections; a central coiled-coil rod domain, N and C-terminal globular region and exhibits a dumbbell like structure <ref>PMID:3430617</ref>. C-terminal region is composed of 6 homologous repeating domains, and this region has a role in binding to intermediate filaments such as vimentin and cytokeratin (2). N-terminal globular region contains actin binding domain (ABD) comprising two calponin homology (CH) domains and N-terminal arm, which varies among isoforms (3). |
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| + | For more details see [[Group:MUZIC:Plectin]]. | ||
==3D structures of plectin== | ==3D structures of plectin== | ||
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[[4q57]] - hPCN actin-binding domain + calmodulin N terminal<br /> | [[4q57]] - hPCN actin-binding domain + calmodulin N terminal<br /> | ||
| - | + | == References == | |
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 08:16, 5 July 2016
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