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2n7b
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR structure of human I-type lectin domain-glycan complex== | |
| - | + | <StructureSection load='2n7b' size='340' side='right' caption='[[2n7b]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2n7b]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N7B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0D8:3-AMINOPROPAN-1-OL'>0D8</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=G6S:D-GALACTOSE-6-SULFATE'>G6S</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2n7a|2n7a]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n7b OCA], [http://pdbe.org/2n7b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n7b RCSB], [http://www.ebi.ac.uk/pdbsum/2n7b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2n7b ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SIGL8_HUMAN SIGL8_HUMAN]] Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Allain, F H.T]] | ||
| + | [[Category: Ernst, B]] | ||
| + | [[Category: Proepster, J M]] | ||
[[Category: Rabbani, S]] | [[Category: Rabbani, S]] | ||
| - | [[Category: Ernst, B]] | ||
| - | [[Category: Proepster, J.M]] | ||
| - | [[Category: Allain, F.H.-T]] | ||
[[Category: Schubert, M]] | [[Category: Schubert, M]] | ||
[[Category: Yang, F]] | [[Category: Yang, F]] | ||
| + | [[Category: Carbohydrate recognition]] | ||
| + | [[Category: Carbohydrate-binding receptor]] | ||
| + | [[Category: I-type lectin]] | ||
| + | [[Category: Protein-glycan complex]] | ||
| + | [[Category: Saf-2]] | ||
| + | [[Category: Sialic acid-binding immunoglobulin-like lectin 8]] | ||
| + | [[Category: Siglec8]] | ||
| + | [[Category: Structural protein]] | ||
| + | [[Category: Sulfated sialyl lewis x]] | ||
Revision as of 17:53, 13 July 2016
NMR structure of human I-type lectin domain-glycan complex
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Categories: Allain, F H.T | Ernst, B | Proepster, J M | Rabbani, S | Schubert, M | Yang, F | Carbohydrate recognition | Carbohydrate-binding receptor | I-type lectin | Protein-glycan complex | Saf-2 | Sialic acid-binding immunoglobulin-like lectin 8 | Siglec8 | Structural protein | Sulfated sialyl lewis x
