5d4d
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Thermus thermophilus product complex for transcription initiation with NAD and CTP== | |
| - | + | <StructureSection load='5d4d' size='340' side='right' caption='[[5d4d]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5d4d]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/ ], [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] and [http://en.wikipedia.org/wiki/Thermus_thermophilus_(strain_hb8_/_atcc_27634_/_dsm_579) Thermus thermophilus (strain hb8 / atcc 27634 / dsm 579)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D4D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D4D FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4g7h|4g7h]], [[5d4e|5d4e]], [[5d4c|5d4c]]</td></tr> |
| - | [[Category: Ebright, R | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d4d OCA], [http://pdbe.org/5d4d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d4d RCSB], [http://www.ebi.ac.uk/pdbsum/5d4d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d4d ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RPOZ_THET8 RPOZ_THET8]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). [[http://www.uniprot.org/uniprot/RPOA_THETH RPOA_THETH]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOC_THET8 RPOC_THET8]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/RPOB_THET8 RPOB_THET8]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. [[http://www.uniprot.org/uniprot/SIGA_THET2 SIGA_THET2]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.[HAMAP-Rule:MF_00963] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: DNA-directed RNA polymerase]] | ||
| + | [[Category: Thermus thermophilus]] | ||
| + | [[Category: Ebright, R H]] | ||
[[Category: Zhang, Y]] | [[Category: Zhang, Y]] | ||
| + | [[Category: Bacterial]] | ||
| + | [[Category: Dna]] | ||
| + | [[Category: Dna-directed rna polymerase]] | ||
| + | [[Category: Gene expression regulation]] | ||
| + | [[Category: Genetic]] | ||
| + | [[Category: Ncin]] | ||
| + | [[Category: Non-canonical initiating nucleotide]] | ||
| + | [[Category: Primer-dependent initiation]] | ||
| + | [[Category: Promoter region]] | ||
| + | [[Category: Protein conformation]] | ||
| + | [[Category: Rna polymerase]] | ||
| + | [[Category: Sigma factor]] | ||
| + | [[Category: Single-stranded]] | ||
| + | [[Category: Transcription initiation]] | ||
| + | [[Category: Transcription-dna complex]] | ||
Revision as of 17:57, 13 July 2016
Crystal structure of Thermus thermophilus product complex for transcription initiation with NAD and CTP
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Categories: DNA-directed RNA polymerase | Thermus thermophilus | Ebright, R H | Zhang, Y | Bacterial | Dna | Dna-directed rna polymerase | Gene expression regulation | Genetic | Ncin | Non-canonical initiating nucleotide | Primer-dependent initiation | Promoter region | Protein conformation | Rna polymerase | Sigma factor | Single-stranded | Transcription initiation | Transcription-dna complex
