This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5l5g
From Proteopedia
(Difference between revisions)
m (Protected "5l5g" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Plexin A2 full extracellular region, domains 1 to 8 modeled, data to 10 angstrom== | |
| - | + | <StructureSection load='5l5g' size='340' side='right' caption='[[5l5g]], [[Resolution|resolution]] 10.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5l5g]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L5G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l5g OCA], [http://pdbe.org/5l5g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l5g RCSB], [http://www.ebi.ac.uk/pdbsum/5l5g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l5g ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PLXA2_MOUSE PLXA2_MOUSE]] Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.<ref>PMID:10520994</ref> <ref>PMID:10781943</ref> <ref>PMID:20877282</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Coles, C H]] | ||
| + | [[Category: Gilbert, R J.C]] | ||
| + | [[Category: Janssen, B J.C]] | ||
| + | [[Category: Jones, E Y]] | ||
| + | [[Category: Kaufmann, R]] | ||
| + | [[Category: Kong, Y]] | ||
| + | [[Category: Malinauskas, T]] | ||
| + | [[Category: Ni, T]] | ||
| + | [[Category: Padilla-Parra, S]] | ||
| + | [[Category: Pasterkamp, R J]] | ||
| + | [[Category: Vangoor, V R]] | ||
| + | [[Category: Axon guidance]] | ||
| + | [[Category: Receptor]] | ||
| + | [[Category: Signaling]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 18:05, 13 July 2016
Plexin A2 full extracellular region, domains 1 to 8 modeled, data to 10 angstrom
| |||||||||||
