5l5k
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Plexin A4 full extracellular region, domains 1 to 10, data to 7.5 angstrom, spacegroup P4(1)== | |
| - | + | <StructureSection load='5l5k' size='340' side='right' caption='[[5l5k]], [[Resolution|resolution]] 7.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5l5k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L5K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L5K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l5k OCA], [http://pdbe.org/5l5k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l5k RCSB], [http://www.ebi.ac.uk/pdbsum/5l5k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l5k ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PLXA4_MOUSE PLXA4_MOUSE]] Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.<ref>PMID:12591607</ref> <ref>PMID:18262512</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Coles, C H]] | ||
| + | [[Category: Gilbert, R J.C]] | ||
| + | [[Category: Janssen, B J.C]] | ||
| + | [[Category: Jones, E Y]] | ||
| + | [[Category: Kaufmann, R]] | ||
| + | [[Category: Kong, Y]] | ||
| + | [[Category: Malinauskas, T]] | ||
| + | [[Category: Ni, T]] | ||
| + | [[Category: Padilla-Parra, S]] | ||
| + | [[Category: Pasterkamp, R J]] | ||
| + | [[Category: Vangoor, V R]] | ||
| + | [[Category: Axon guidance]] | ||
| + | [[Category: Receptor]] | ||
| + | [[Category: Signaling]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 18:05, 13 July 2016
Plexin A4 full extracellular region, domains 1 to 10, data to 7.5 angstrom, spacegroup P4(1)
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