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5lba
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human RECQL5 helicase in complex with DSPL fragment(1-cyclohexyl-3-(oxolan-2-ylmethyl)urea, SGC - Diamond XChem I04-1 fragment screening.== | |
| - | + | <StructureSection load='5lba' size='340' side='right' caption='[[5lba]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5lba]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LBA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6SV:1-CYCLOHEXYL-3-[[(2~{R})-OXOLAN-2-YL]METHYL]UREA'>6SV</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lba OCA], [http://pdbe.org/5lba PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lba RCSB], [http://www.ebi.ac.uk/pdbsum/5lba PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lba ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RECQ5_HUMAN RECQ5_HUMAN]] May have an important role in DNA metabolism. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: DNA helicase]] | ||
[[Category: Aitkenhead, H]] | [[Category: Aitkenhead, H]] | ||
| - | [[Category: | + | [[Category: Arrowsmith, C H]] |
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
| - | [[Category: | + | [[Category: Delft, F Von]] |
| - | + | [[Category: Edwards, A M]] | |
| - | [[Category: Edwards, A | + | |
| - | + | ||
[[Category: Gileadi, O]] | [[Category: Gileadi, O]] | ||
| - | [[Category: Newman, J | + | [[Category: Krojer, T]] |
| - | [[Category: Structural | + | [[Category: Newman, J A]] |
| + | [[Category: Structural genomic]] | ||
[[Category: Savitsky, P]] | [[Category: Savitsky, P]] | ||
| + | [[Category: Talon, R]] | ||
| + | [[Category: Diamond i04-1 xchem]] | ||
| + | [[Category: Fragment screening]] | ||
| + | [[Category: Helicase]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Recq]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 18:06, 13 July 2016
Crystal structure of human RECQL5 helicase in complex with DSPL fragment(1-cyclohexyl-3-(oxolan-2-ylmethyl)urea, SGC - Diamond XChem I04-1 fragment screening.
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