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5e1a
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of KcsA with L24C/R117C mutations== | |
| - | + | <StructureSection load='5e1a' size='340' side='right' caption='[[5e1a]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5e1a]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E1A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E1A FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e1a OCA], [http://pdbe.org/5e1a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e1a RCSB], [http://www.ebi.ac.uk/pdbsum/5e1a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e1a ProSAT]</span></td></tr> |
| - | [[Category: Kim, D | + | </table> |
| - | [[Category: Nimigean, C | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI]] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Kim, D M]] | ||
| + | [[Category: Nimigean, C M]] | ||
[[Category: Upadhyay, V]] | [[Category: Upadhyay, V]] | ||
| + | [[Category: Kcsa]] | ||
| + | [[Category: Metal transport]] | ||
| + | [[Category: Mutation]] | ||
| + | [[Category: Potassium channel]] | ||
| + | [[Category: Proton]] | ||
Revision as of 11:43, 14 July 2016
Structure of KcsA with L24C/R117C mutations
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Categories: Mus musculus | Kim, D M | Nimigean, C M | Upadhyay, V | Kcsa | Metal transport | Mutation | Potassium channel | Proton
