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5e9j

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'''Unreleased structure'''
 
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The entry 5e9j is ON HOLD until Paper Publication
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==Crystal structure of the mRNA cap guanine-N7 methyltransferase - modular lobe (416-456) deletion==
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<StructureSection load='5e9j' size='340' side='right' caption='[[5e9j]], [[Resolution|resolution]] 3.47&Aring;' scene=''>
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Authors: PETIT, P., COWLING, V.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5e9j]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E9J FirstGlance]. <br>
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Description: Crystal structure of the mRNA cap guanine-N7 methyltransferase -modular lobe (416-456) deletion
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5e8j|5e8j]]</td></tr>
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[[Category: Petit, P]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e9j OCA], [http://pdbe.org/5e9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e9j RCSB], [http://www.ebi.ac.uk/pdbsum/5e9j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e9j ProSAT]</span></td></tr>
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[[Category: Cowling, V.H]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MCES_HUMAN MCES_HUMAN]] mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.<ref>PMID:9790902</ref> <ref>PMID:9705270</ref> <ref>PMID:10347220</ref> <ref>PMID:22099306</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: COWLING, V H]]
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[[Category: PETIT, P]]
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[[Category: Mrna capping]]
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[[Category: Rna processing]]
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[[Category: Transferase]]

Revision as of 11:43, 14 July 2016

Crystal structure of the mRNA cap guanine-N7 methyltransferase - modular lobe (416-456) deletion

5e9j, resolution 3.47Å

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