1k4h

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|PDB= 1k4h |SIZE=350|CAPTION= <scene name='initialview01'>1k4h</scene>, resolution 1.80&Aring;
|PDB= 1k4h |SIZE=350|CAPTION= <scene name='initialview01'>1k4h</scene>, resolution 1.80&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=APQ:2,6-DIAMINO-8-PROPYLSULFANYLMETHYL-3H-QUINAZOLINE-4-ONE'>APQ</scene>
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|LIGAND= <scene name='pdbligand=APQ:2,6-DIAMINO-8-PROPYLSULFANYLMETHYL-3H-QUINAZOLINE-4-ONE'>APQ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Queuine_tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Queuine_tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] </span>
|GENE=
|GENE=
 +
|DOMAIN=
 +
|RELATEDENTRY=[[1enu|1ENU]], [[1pud|1PUD]], [[1f3e|1F3E]], [[1k4g|1K4G]]
 +
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k4h OCA], [http://www.ebi.ac.uk/pdbsum/1k4h PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1k4h RCSB]</span>
}}
}}
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[[Category: Meyer, E A.]]
[[Category: Meyer, E A.]]
[[Category: Stubbs, M T.]]
[[Category: Stubbs, M T.]]
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[[Category: APQ]]
 
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[[Category: ZN]]
 
[[Category: glycosyltransferase]]
[[Category: glycosyltransferase]]
[[Category: trna-modifying enzyme]]
[[Category: trna-modifying enzyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:12:29 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:43:19 2008''

Revision as of 18:43, 30 March 2008


PDB ID 1k4h

Drag the structure with the mouse to rotate
, resolution 1.80Å
Ligands: ,
Activity: Queuine tRNA-ribosyltransferase, with EC number 2.4.2.29
Related: 1ENU, 1PUD, 1F3E, 1K4G


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH 2,6-Diamino-8-propylsulfanylmethyl-3H-quinazoline-4-one


About this Structure

1K4H is a Single protein structure of sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.

Reference

De novo design, synthesis, and in vitro evaluation of inhibitors for prokaryotic tRNA-guanine transglycosylase: a dramatic sulfur effect on binding affinity., Meyer EA, Brenk R, Castellano RK, Furler M, Klebe G, Diederich F, Chembiochem. 2002 Mar 1;3(2-3):250-3. PMID:11921407

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