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4zcw
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Human Enolase 2 in complex with SF2312== | |
| - | + | <StructureSection load='4zcw' size='340' side='right' caption='[[4zcw]], [[Resolution|resolution]] 1.99Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4zcw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZCW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZCW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4NG:[(3S,5S)-1,5-DIHYDROXY-2-OXOPYRROLIDIN-3-YL]PHOSPHONIC+ACID'>4NG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4za0|4za0]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zcw OCA], [http://pdbe.org/4zcw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zcw RCSB], [http://www.ebi.ac.uk/pdbsum/4zcw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zcw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ENOG_HUMAN ENOG_HUMAN]] Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Phosphopyruvate hydratase]] | ||
[[Category: Czako, B]] | [[Category: Czako, B]] | ||
| + | [[Category: Leonard, P G]] | ||
[[Category: Maxwell, D]] | [[Category: Maxwell, D]] | ||
| - | [[Category: Muller, F | + | [[Category: Muller, F L]] |
| - | [[Category: | + | [[Category: Enolase gamma]] |
| + | [[Category: Glycolysis]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Lyase-lyase inhibitor complex]] | ||
| + | [[Category: Neuron specific enolase]] | ||
Revision as of 15:24, 26 July 2016
Structure of Human Enolase 2 in complex with SF2312
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