5cgb

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'''Unreleased structure'''
 
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The entry 5cgb is ON HOLD until Paper Publication
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==Crystal structure of FimH in complex with heptyl alpha-D-septanoside==
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<StructureSection load='5cgb' size='340' side='right' caption='[[5cgb]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5cgb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CGB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CGB FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=51C:(6R)-1,6-ANHYDRO-2-O-HEPTYL-6-(HYDROXYMETHYL)-D-GALACTITOL'>51C</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cgb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cgb OCA], [http://pdbe.org/5cgb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cgb RCSB], [http://www.ebi.ac.uk/pdbsum/5cgb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cgb ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
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__TOC__
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</StructureSection>
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[[Category: Ernst, B]]
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[[Category: Fiege, B]]
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[[Category: Jakob, R P]]
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[[Category: Maier, T]]
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[[Category: Peczuh, M]]
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[[Category: Preston, R P]]
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[[Category: Rabbani, S]]
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[[Category: Sager, C P]]
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[[Category: Vannam, R]]
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[[Category: Zalewski, A]]
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[[Category: Zihlmann, P]]
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[[Category: Inhibitor]]
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[[Category: Lectin]]
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[[Category: Pilus]]
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[[Category: Sugar binding protein]]
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[[Category: Type 1 fimbriae]]
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[[Category: Urinary tract infection]]
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[[Category: Uti]]

Revision as of 15:27, 26 July 2016

Crystal structure of FimH in complex with heptyl alpha-D-septanoside

5cgb, resolution 1.60Å

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