5cnx

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'''Unreleased structure'''
 
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The entry 5cnx is ON HOLD until Paper Publication
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==Crystal structure of Xaa-Pro aminopeptidase from Escherichia coli K12==
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<StructureSection load='5cnx' size='340' side='right' caption='[[5cnx]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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Authors: Kumar, A., Are, V., Ghosh, B., Jamdar, S., Makde, R.D.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5cnx]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CNX FirstGlance]. <br>
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Description: Crystal structure of Xaa-Pro aminopeptidase from Escherichia coli K12
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cnx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cnx OCA], [http://pdbe.org/5cnx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cnx RCSB], [http://www.ebi.ac.uk/pdbsum/5cnx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cnx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/YPDF_ECOLI YPDF_ECOLI]] Hydrolyzes the N-terminal methionine when the next amino acid is alanine, proline or serine. The substrate preference for methionyl aminopeptidase activity is Pro > Ala > Ser. Also able to hydrolyze the Xaa-Pro peptide bond when the first amino acid is alanine, asparagine or methionine.<ref>PMID:15901689</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Are, V]]
[[Category: Are, V]]
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[[Category: Makde, R.D]]
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[[Category: Ghosh, B]]
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[[Category: Jamdar, S]]
[[Category: Kumar, A]]
[[Category: Kumar, A]]
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[[Category: Jamdar, S]]
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[[Category: Makde, R D]]
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[[Category: Ghosh, B]]
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[[Category: Hydrolase]]
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[[Category: Pepq]]
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[[Category: Prolidase]]
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[[Category: Xaa-pro aminopeptidase]]

Revision as of 15:29, 26 July 2016

Crystal structure of Xaa-Pro aminopeptidase from Escherichia coli K12

5cnx, resolution 2.60Å

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