5d0u
From Proteopedia
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==Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP== | ==Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP== | ||
<StructureSection load='5d0u' size='340' side='right' caption='[[5d0u]], [[Resolution|resolution]] 2.92Å' scene=''> | <StructureSection load='5d0u' size='340' side='right' caption='[[5d0u]], [[Resolution|resolution]] 2.92Å' scene=''> | ||
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<table><tr><td colspan='2'>[[5d0u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D0U FirstGlance]. <br> | <table><tr><td colspan='2'>[[5d0u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D0U FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d0u OCA], [http://pdbe.org/5d0u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d0u RCSB], [http://www.ebi.ac.uk/pdbsum/5d0u PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d0u OCA], [http://pdbe.org/5d0u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d0u RCSB], [http://www.ebi.ac.uk/pdbsum/5d0u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d0u ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | RNA helicases are indispensable for all organisms in each domain of life and have implications in numerous cellular processes. The DEAH-box RNA helicase Prp43 is involved in pre-mRNA splicing as well as rRNA maturation. Here, the crystal structure of Chaetomium thermophilum Prp43 at 2.9 A resolution is revealed. Furthermore, it is demonstrated that Prp43 from C. thermophilum is capable of functionally replacing its orthologue from Saccharomyces cerevisiae in spliceosomal disassembly assays. | ||
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| + | Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum.,Tauchert MJ, Fourmann JB, Christian H, Luhrmann R, Ficner R Acta Crystallogr F Struct Biol Commun. 2016 Feb;72(Pt 2):112-20. doi:, 10.1107/S2053230X15024498. Epub 2016 Jan 22. PMID:26841761<ref>PMID:26841761</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 5d0u" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 08:07, 27 July 2016
Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP
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