1kaw

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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kaw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kaw OCA], [http://www.ebi.ac.uk/pdbsum/1kaw PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1kaw RCSB]</span>
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[[Category: ssb]]
[[Category: ssb]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:14:53 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:45:53 2008''

Revision as of 18:45, 30 March 2008


PDB ID 1kaw

Drag the structure with the mouse to rotate
, resolution 2.9Å
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



STRUCTURE OF SINGLE STRANDED DNA BINDING PROTEIN (SSB)


Overview

The crystal structure of the tetrameric DNA-binding domain of the single-stranded DNA binding protein from Escherichia coli was determined at a resolution of 2.9 A using multiwavelength anomalous dispersion. Each monomer in the tetramer is topologically similar to an oligomer-binding fold. Two monomers each contribute three beta-strands to a single six-stranded beta-sheet to form a dimer. Two dimer-dimer interfaces are observed within the crystal. One of these stabilizes the tetramer in solution. The other interface promotes a superhelical structure within the crystal that may reflect tetramer-tetramer interactions involved in the positive cooperative binding of the single-stranded DNA-binding protein to single-stranded DNA.

About this Structure

1KAW is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution., Raghunathan S, Ricard CS, Lohman TM, Waksman G, Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6652-7. PMID:9192620

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