Purine repressor
From Proteopedia
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<StructureSection load='1qp4' size='350' side='right' caption='Structure of purine processor complex with DNA (green) and hypoxanthine (PDB entry [[1qp4]])' scene=''> | <StructureSection load='1qp4' size='350' side='right' caption='Structure of purine processor complex with DNA (green) and hypoxanthine (PDB entry [[1qp4]])' scene=''> | ||
| - | + | == Function == | |
| - | '''Purine repressor''' (PurR) is a member of the lac repressor family. PurP binds DNA via a highly conserved helix-turn-helix at the N terminal (DBD). PurP contains a co-repressor binding domain as well (CBD). PurP binds to a 16-bp operator sequence and co-regulates genes which are involved in the biosynthesis of purine and pyrimidine nucleotides. | + | '''Purine repressor''' (PurR) is a member of the lac repressor family. PurP binds DNA via a highly conserved helix-turn-helix at the N terminal (DBD). PurP contains a co-repressor binding domain as well (CBD). PurP binds to a 16-bp operator sequence and co-regulates genes which are involved in the biosynthesis of purine and pyrimidine nucleotides<ref>PMID:1971621</ref>. |
</StructureSection> | </StructureSection> | ||
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**[[1zay]] - EcPurR + DNA + hypoxanthine + di-imino-purine<br /> | **[[1zay]] - EcPurR + DNA + hypoxanthine + di-imino-purine<br /> | ||
}} | }} | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:32, 31 July 2016
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3D structures of purine repressor
Updated on 31-July-2016
References
- ↑ Wilson HR, Turnbough CL Jr. Role of the purine repressor in the regulation of pyrimidine gene expression in Escherichia coli K-12. J Bacteriol. 1990 Jun;172(6):3208-13. PMID:1971621
