Pyridoxal kinase
From Proteopedia
(Difference between revisions)
| Line 18: | Line 18: | ||
**[[1lhp]] – sPDX – sheep<br /> | **[[1lhp]] – sPDX – sheep<br /> | ||
**[[2f7k]] – hPDX - human<br /> | **[[2f7k]] – hPDX - human<br /> | ||
| - | **[[2ddm]] – | + | **[[2ddm]] – EcPDX1 – ''Escherichia coli''<br /> |
**[[3h74]] – LpPDX – ''Lactobacillus planarum'' <br /> | **[[3h74]] – LpPDX – ''Lactobacillus planarum'' <br /> | ||
**[[3zs7]] – PDX – ''Trypanosoma brucei'' <br /> | **[[3zs7]] – PDX – ''Trypanosoma brucei'' <br /> | ||
| Line 27: | Line 27: | ||
**[[1rft]] – sPDX + Zn + K + AMPPCP + pyridoxamine<br /> | **[[1rft]] – sPDX + Zn + K + AMPPCP + pyridoxamine<br /> | ||
**[[1rfu]] – sPDX + Zn + ADP + pyridoxal-5’-phosphate<br /> | **[[1rfu]] – sPDX + Zn + ADP + pyridoxal-5’-phosphate<br /> | ||
| - | **[[2ddw]] – | + | **[[2ddw]] – EcPDX1 + pyridoxal<br /> |
**[[4c5l]] – SaPDX + pyridoxal<br /> | **[[4c5l]] – SaPDX + pyridoxal<br /> | ||
**[[4c5n]] – SaPDX + pyridoxal + AMPPCP<br /> | **[[4c5n]] – SaPDX + pyridoxal + AMPPCP<br /> | ||
Revision as of 09:13, 1 August 2016
Contents |
Function
Pyridoxal kinase (PDX) catalyzes the transfer of phosphate (Pi) from ATP to 5’ alcohol of pyridoxine, pyridoxamine and pyridoxal[1].
Structural highlights
PDX1 active site[2].
3D Structures of pyridoxal kinase
Updated on 01-August-2016
References
- ↑ di Salvo ML, Nogues I, Parroni A, Tramonti A, Milano T, Pascarella S, Contestabile R. On the mechanism of Escherichia coli pyridoxal kinase inhibition by pyridoxal and pyridoxal 5'-phosphate. Biochim Biophys Acta. 2015 Sep;1854(9):1160-6. doi: 10.1016/j.bbapap.2015.01.013., Epub 2015 Feb 3. PMID:25655354 doi:http://dx.doi.org/10.1016/j.bbapap.2015.01.013
- ↑ Safo MK, Musayev FN, di Salvo ML, Hunt S, Claude JB, Schirch V. Crystal structure of pyridoxal kinase from the Escherichia coli pdxK gene: implications for the classification of pyridoxal kinases. J Bacteriol. 2006 Jun;188(12):4542-52. PMID:16740960 doi:188/12/4542
