4ajm
From Proteopedia
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==Development of a plate-based optical biosensor methodology to identify PDE10 fragment inhibitors== | ==Development of a plate-based optical biosensor methodology to identify PDE10 fragment inhibitors== | ||
<StructureSection load='4ajm' size='340' side='right' caption='[[4ajm]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='4ajm' size='340' side='right' caption='[[4ajm]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ajm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4ajm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AJM FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3A6:3-AMINO-6-FLUORO-2-[4-(2-METHYLPYRIDIN-4-YL)PHENYL]-N-(METHYLSULFONYL)QUINOLINE-4-CARBOXAMIDE'>3A6</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3A6:3-AMINO-6-FLUORO-2-[4-(2-METHYLPYRIDIN-4-YL)PHENYL]-N-(METHYLSULFONYL)QUINOLINE-4-CARBOXAMIDE'>3A6</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lrb|1lrb]], [[2wey|2wey]], [[2y0j|2y0j]], [[4ael|4ael]], [[4ajd|4ajd]], [[4ajf|4ajf]], [[4ajg|4ajg]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lrb|1lrb]], [[2wey|2wey]], [[2y0j|2y0j]], [[4ael|4ael]], [[4ajd|4ajd]], [[4ajf|4ajf]], [[4ajg|4ajg]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ajm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ajm RCSB], [http://www.ebi.ac.uk/pdbsum/4ajm PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ajm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajm OCA], [http://pdbe.org/4ajm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ajm RCSB], [http://www.ebi.ac.uk/pdbsum/4ajm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ajm ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Aharony, D]] | [[Category: Aharony, D]] | ||
[[Category: Akerud, T]] | [[Category: Akerud, T]] | ||
Revision as of 07:47, 4 August 2016
Development of a plate-based optical biosensor methodology to identify PDE10 fragment inhibitors
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Categories: Human | Aharony, D | Akerud, T | Albert, J S | Back, E | Geschwindner, S | Hillertz, P | Horsefeld, R | Johansson, P | Scott, C | Spadola, L | Spear, N | Tian, G | Tigerstrom, A | Hydrolase
