4gmd
From Proteopedia
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| ==The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with AZT Monophosphate== | ==The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with AZT Monophosphate== | ||
| <StructureSection load='4gmd' size='340' side='right' caption='[[4gmd]], [[Resolution|resolution]] 1.98Å' scene=''> | <StructureSection load='4gmd' size='340' side='right' caption='[[4gmd]], [[Resolution|resolution]] 1.98Å' scene=''> | ||
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4gmd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4gmd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GMD FirstGlance]. <br> | 
| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATM:3-AZIDO-3-DEOXYTHYMIDINE-5-MONOPHOSPHATE'>ATM</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATM:3-AZIDO-3-DEOXYTHYMIDINE-5-MONOPHOSPHATE'>ATM</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e5u|4e5u]], [[4edh|4edh]], [[4esh|4esh]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e5u|4e5u]], [[4edh|4edh]], [[4esh|4esh]]</td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA2962, tmk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PA2962, tmk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr> | 
| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gmd RCSB], [http://www.ebi.ac.uk/pdbsum/4gmd PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gmd OCA], [http://pdbe.org/4gmd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gmd RCSB], [http://www.ebi.ac.uk/pdbsum/4gmd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gmd ProSAT]</span></td></tr> | 
| </table> | </table> | ||
| == Function == | == Function == | ||
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| __TOC__ | __TOC__ | ||
| </StructureSection> | </StructureSection> | ||
| - | [[Category:  | + | [[Category: Pseae]] | 
| [[Category: DTMP kinase]] | [[Category: DTMP kinase]] | ||
| [[Category: Jedrzejczak, R]] | [[Category: Jedrzejczak, R]] | ||
Revision as of 08:35, 4 August 2016
The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with AZT Monophosphate
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Categories: Pseae | DTMP kinase | Jedrzejczak, R | Joachimiak, A | Joachimiak, G | Structural genomic | MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors | Sacchettini, J | Tan, K | Mcsg | Mtbi | PSI, Protein structure initiative | Psi-biology | Structures of mtb proteins conferring susceptibility to known mtb inhibitor | Transferase | Transferase-inhibitor complex
