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==Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAM==
==Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAM==
<StructureSection load='4gon' size='340' side='right' caption='[[4gon]], [[Resolution|resolution]] 2.72&Aring;' scene=''>
<StructureSection load='4gon' size='340' side='right' caption='[[4gon]], [[Resolution|resolution]] 2.72&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b3387, dam, JW3350 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b3387, dam, JW3350 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Site-specific_DNA-methyltransferase_(adenine-specific) Site-specific DNA-methyltransferase (adenine-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.72 2.1.1.72] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Site-specific_DNA-methyltransferase_(adenine-specific) Site-specific DNA-methyltransferase (adenine-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.72 2.1.1.72] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gon OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gon RCSB], [http://www.ebi.ac.uk/pdbsum/4gon PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gon OCA], [http://pdbe.org/4gon PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gon RCSB], [http://www.ebi.ac.uk/pdbsum/4gon PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gon ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DMA_ECOLI DMA_ECOLI]] Methylates DNA within the sequence GATC and protects the DNA from cleavage by the restriction endonuclease MboI. Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in postreplication mismatch repair rather than as a part of a restriction modification system. May also play a role in DNA replication.
[[http://www.uniprot.org/uniprot/DMA_ECOLI DMA_ECOLI]] Methylates DNA within the sequence GATC and protects the DNA from cleavage by the restriction endonuclease MboI. Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in postreplication mismatch repair rather than as a part of a restriction modification system. May also play a role in DNA replication.
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==See Also==
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*[[DNA adenine methylase|DNA adenine methylase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Revision as of 11:31, 4 August 2016

Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAM

4gon, resolution 2.72Å

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