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2x9e

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==HUMAN MPS1 IN COMPLEX WITH NMS-P715==
==HUMAN MPS1 IN COMPLEX WITH NMS-P715==
<StructureSection load='2x9e' size='340' side='right' caption='[[2x9e]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
<StructureSection load='2x9e' size='340' side='right' caption='[[2x9e]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2x9e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X9E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X9E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2x9e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X9E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X9E FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SVE:N-(2,6-DIETHYLPHENYL)-1-METHYL-8-({4-[(1-METHYLPIPERIDIN-4-YL)CARBAMOYL]-2-(TRIFLUOROMETHOXY)PHENYL}AMINO)-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE'>SVE</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SVE:N-(2,6-DIETHYLPHENYL)-1-METHYL-8-({4-[(1-METHYLPIPERIDIN-4-YL)CARBAMOYL]-2-(TRIFLUOROMETHOXY)PHENYL}AMINO)-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE'>SVE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hmo|3hmo]], [[3hmp|3hmp]], [[3h9f|3h9f]], [[3hmn|3hmn]], [[3gfw|3gfw]], [[2zmc|2zmc]], [[3cek|3cek]], [[2zmd|2zmd]], [[3dbq|3dbq]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hmo|3hmo]], [[3hmp|3hmp]], [[3h9f|3h9f]], [[3hmn|3hmn]], [[3gfw|3gfw]], [[2zmc|2zmc]], [[3cek|3cek]], [[2zmd|2zmd]], [[3dbq|3dbq]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dual-specificity_kinase Dual-specificity kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.12.1 2.7.12.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dual-specificity_kinase Dual-specificity kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.12.1 2.7.12.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x9e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x9e RCSB], [http://www.ebi.ac.uk/pdbsum/2x9e PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x9e OCA], [http://pdbe.org/2x9e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x9e RCSB], [http://www.ebi.ac.uk/pdbsum/2x9e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x9e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2x9e" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Dual-specificity kinase]]
[[Category: Dual-specificity kinase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Avanzi, N]]
[[Category: Avanzi, N]]
[[Category: Bertrand, J A]]
[[Category: Bertrand, J A]]

Revision as of 13:20, 4 August 2016

HUMAN MPS1 IN COMPLEX WITH NMS-P715

2x9e, resolution 3.10Å

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