4bky

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
 +
==Crystal structure of unphosphorylated Maternal Embryonic Leucine zipper Kinase (MELK) in complex with pyrrolopyrazole inhibitor==
==Crystal structure of unphosphorylated Maternal Embryonic Leucine zipper Kinase (MELK) in complex with pyrrolopyrazole inhibitor==
<StructureSection load='4bky' size='340' side='right' caption='[[4bky]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
<StructureSection load='4bky' size='340' side='right' caption='[[4bky]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4bky]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BKY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BKY FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4bky]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BKY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BKY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=82B:3-{[(4-BROMO-1-METHYL-1H-PYRROL-2-YL)CARBONYL]AMINO}-N-[(1S)-1-PHENYL-2-(PYRROLIDIN-1-YL)ETHYL]-1,4-DIHYDRO-5H-SPIRO[CYCLOPROPANE-1,6-PYRROLO[3,4-C]PYRAZOLE]-5-CARBOXAMIDE'>82B</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=82B:3-{[(4-BROMO-1-METHYL-1H-PYRROL-2-YL)CARBONYL]AMINO}-N-[(1S)-1-PHENYL-2-(PYRROLIDIN-1-YL)ETHYL]-1,4-DIHYDRO-5H-SPIRO[CYCLOPROPANE-1,6-PYRROLO[3,4-C]PYRAZOLE]-5-CARBOXAMIDE'>82B</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bkz|4bkz]], [[4bl1|4bl1]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bkz|4bkz]], [[4bl1|4bl1]]</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bky OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bky RCSB], [http://www.ebi.ac.uk/pdbsum/4bky PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bky OCA], [http://pdbe.org/4bky PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bky RCSB], [http://www.ebi.ac.uk/pdbsum/4bky PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bky ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
Line 19: Line 20:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4bky" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Homo sapiens]]
+
[[Category: Human]]
[[Category: Bertrand, J A]]
[[Category: Bertrand, J A]]
[[Category: Canevari, G]]
[[Category: Canevari, G]]

Revision as of 14:53, 4 August 2016

Crystal structure of unphosphorylated Maternal Embryonic Leucine zipper Kinase (MELK) in complex with pyrrolopyrazole inhibitor

4bky, resolution 1.83Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools